Biocatalysis for the Pharmaceutical Industry: Discovery, Development, and Manufacturing by Junhua Tao, Guo-Qiang Lin, Andreas Liese
Wiley | 2008 | ISBN: 0470823143 | 250 pages | PDF | 14 MB
Biocatalysis
is rapidly evolving into a key technology for the discovery and
production of chemicals, especially in the pharmaceutical industry,
where high yielding chemo-, regio-, and enantioselective reactions are
critical. Taking the latest breakthroughs in genomics and proteomics
into consideration, Biocatalysis for the Pharmaceutical Industry
concisely yet comprehensively discusses the modern application of
biocatalysis to drug discovery, development, and manufacturing. Written
by a team of leading experts, the book offers deep insight into this
cutting edge field.
* Covers a wide range of topics in a systematic manner with an emphasis on industrial applications
*
Provides a thorough introduction to the latest biocatalysts, modern
expression hosts, state-of-the-art directed evolution, high throughput
screening, and bioprocess engineering
* Addresses frontier subjects
such as emerging enzymes, metabolite profiling, combinatorial
biosynthesis, metabolic engineering, and autonomous enzymes for the
synthesis and development of chiral molecules, drug metabolites, and
semi-synthetic medicinal compounds and natural product analogs
* Highlights the impact of biocatalysis on green chemistry
* Contains numerous graphics to illustrate concepts and techniques
Biocatalysis
for the Pharmaceutical Industry is an essential resource for
scientists, engineers, and R&D policy makers in the fine chemical,
pharmaceutical, and biotech industries. It is also an invaluable tool
for academic researchers and advanced students of organic and materials
synthesis, chemical biology, and medicinal chemistry.